Inhibition of the insulin-like growth factor-1 receptor (IGF1R) tyrosine kinase as a novel cancer therapy approach

J Med Chem. 2009 Aug 27;52(16):4981-5004. doi: 10.1021/jm9002395.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Animals
  • Antineoplastic Agents / chemistry*
  • Antineoplastic Agents / pharmacology
  • Drug Resistance, Neoplasm
  • Humans
  • Neoplasms / drug therapy
  • Neoplasms / enzymology*
  • Receptor, IGF Type 1 / antagonists & inhibitors*
  • Receptor, IGF Type 1 / biosynthesis
  • Receptor, IGF Type 1 / physiology
  • Signal Transduction

Substances

  • Antineoplastic Agents
  • Receptor, IGF Type 1